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While significant adverse events are uncommon at research-appropriate doses, it's prudent to monitor for any unexpected physiological changes

[DOI] [PubMed] [Google Scholar] Spasojevi I., Chen Y., Noel T.J., Yu Y., Cole M.P., Zhang L., Zhao Y., St Clair D.K., Batini-Haberle I

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Mice were acclimated to metabolic cage accommodation with a 1-week daily training session of 10 h in identical cages prior to data acquisition, after which mice were returned to their original cages