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The major enzyme superfamilies comprise cytochrome P450 monooxygenases (P450s), glutathione S-transferases (GSTs), carboxylesterases (COEs), ATP-binding cassette (ABC) transporters, and UDP-glycosyltransferases (UGTs) [5, 26, 36-39] (Figure 2)

Key applications of MSM Anti-inflammatory: An anti-inflammatory, MSM helps to lessen pro-inflammatory markers to inhibit inflammation in the body

Antioxid Redox Signal 9:202733, PMID: 17845131 Hinchman CA, Ballatori N (1994) Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process

Tucci et al., 2016

Arginase 1 deficiency Arginase 1 deficiency is an autosomal-recessive disorder

TNF- Promotes synovial inflammation and cartilage bone destruction in rheumatoid arthritis via NF-B/YY1/miR-103a-3p axis