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Hippocampal pdha1 gene knockout inhibits the warburg effect leading to cognitive dysfunction and attenuates the beneficial effects of zibupiyin recipe on cognition

This does not affect product stability or performance

For the hypoxic group, a timer-controlled aerator was utilized for intermittent oxygenation, maintaining dissolved oxygen at approximately 1 mg/L

Proc Natl Acad Sci U S A (2010) 107(36):158805

This allows researchers to track protein localization, study protein-protein interactions via cross-linking, and perform detailed proteomic characterization using mass spectrometry

LC-MS/MS and Co-IP assays indicated that FABP5 is a major target of Grx1 and is susceptible to redox-dependent regulation in response to oxidative stress