glutathione reductase biosensor Rapid and sensitive electrochemical detection of oxidized form of in whole blood samples using Bi-metallic nanocomposites In vivo detection of glutathione

In addition, it has been found that excessive accumulation of iron and zinc ions causes the loss of retinal ganglion cells (RGCs) and that mitochondrial dysfunction caused by excessive accumulation of iron or zinc, including defects in mitochondrial biogenesis and fusion, as well as processes such as fission and an increase in mitochondrial autophagy, constitutes a potential mechanism of glaucoma causation, accelerating the loss of RGCs (41)

Then that T4 has to get converted into T3, because T4 is not very active metabolically

It is well established that T cells shift their metabolism based on their differentiation state and functional capacity: namely, T nave (Tn) and T memory (Tm) cells mainly rely on oxidative phosphorylation (OXPHOS) for their bioenergetic needs, whereas T effector (Te) cells, which are dominantly responsible for tumor killing, are fueled by glycolysis ( Redox metabolism, methionine metabolism, and the general control nonderepressible 2 (GCN2) pathway have all garnered increasing attention in the cancer immunotherapy field as potential therapeutic targets

NeuroImage (2019) 191:17685

Thomas, Emily Todd, Hanya Benotmane, Henrik Zetterberg, Imogen J

These observations identify microRNAs as a promising target to overcome lenvatinib resistance in HCC