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They proposed that melatonin upregulates antioxidant enzymes, increases distribution of cells in S-phase and decreases G0/G1 cells, reduces lipid peroxidation, all of which could explain its protective mechanism [39]

Methionine is an essential amino acid that is primarily metabolized in the liver

Nat Rev Gastroenterol Hepatol (2015) 12:20517

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4.2.3 Regulation of ferroptosis by iron metabolism Ferroptosis can be inhibited by reducing iron uptake and using iron chelators