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A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

doi: Jan 10, 2023 Chisom Okoli, Josephine Shieh, Kassidy Sharpe and Caree Cotwright have a paper published in Childhood Obesity

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are co-founders and shareholders of Aprea Therapeutics AB, a company that develops p53-based cancer therapy

HIF-1 and BMAL1 co-regulate intracellular oxidative stress levels under hypoxic conditions Hypoxia can diminish the osteogenic effect during bone regeneration and proliferation due to its direct suppression of cell activity, as well as its promotion of pro-inflammatory mediators such as ROS