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Growth Hormone (HGH) Replaces GH directly Bypasses pituitary regulation Can suppress endogenous GH production May raise IGF-1 excessively Higher risk of edema, insulin resistance, and carpal tunnel syndrome Tesamorelin Stimulates the pituitary gland Preserves physiologic pulsatility Maintains feedback control Lower risk of GH excess Improves IGF-1 within normal ranges From a functional medicine standpoint, tesamorelin is a restorative therapy , whereas HGH is a replacement therapy

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Its even more vital for pregnant or lactating women who are vegetarian/vegan to consume enough B12, as infants are at higher risk for B12 deficiency (7)

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Higher NNMT levels have also been observed in patients with some forms of muscular dystrophy [12]