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With respect to the cost criterion, to identify potential cases representing patients who may be eligible for TECVAYLI TM , the applicant searched the FY 2021 MedPAR file for cases reporting one of the following ICD-10- ( CM codes in one of the first five diagnosis code positions: C90.00 (Multiple myeloma not having achieved remission), C90.01 (Multiple myeloma in remission), or C90.02 (Multiple myeloma in relapse)

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In addition to apoptosis and necrosis, ferroptosis, an iron dependent and lipid-peroxidation driven cell death (Hambright et al., 2017)

Characterization of the major hydroperoxide-reducing activity of human plasma