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35 HaorahJ.KnipeB.GorantlaS.ZhengJ.PersidskyY

The yeast WD40 and WD40 domains are structural homologs with complete conservation of the binding site except for two residues, i.e., His31/Tyr139 in WD40 are replaced by Tyr33/Phe142 in WD40 61,62 (Supplementary Fig