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However, it appears that these risks are reduced in younger women and when HRT is used soon after menopause (in other words, the risks are higher in older women and when HRT is used longer after menopause)

This could result in low bioavailable levels even if intake of cyanocobalamin meets or exceeds the recommended daily amount

10.1186/s13041-015-0116-z Mol

Individual responses vary, and specific results cannot be guaranteed

While subcutaneous injections are generally well tolerated, some patients experience mild to moderate localized reactions at the injection site

It is only available for prescription use and is administered by injection or, in severe cases, an IV drip