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Structural insights into these variants may inform the development of isoform-specific modulators, aiding therapeutic selectivity in targeting ferritin

B., and da Gama, M

eIF4E and eIF4G1 partake in translation initiation pathways interacting with binding partners and RNA helicases

The biosynthesis of these oxidizable phospholipids is tightly regulated by enzymatic pathways involving ACSL4, which activates AA and AdA into acyl-CoA derivatives, and LPCAT3, which incorporates them into the sn-2 position of phospholipid backbones, especially PCs (Reed et al., 2022)

doi: 10.1016/j.cell.2021.09.020 171 YarchoanMHopkinsAJaffeeEM

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