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Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9

7 Following detachment from the primary tumour, the metastatic process comprises a sequence of steps, including cell invasion through the basement membrane into surrounding tissue, intravasation into blood vessels, survival and arrest in the circulatory system, extravasation through transendothelial migration, colonisation and the eventual formation of distant metastatic lesions (Fig

doi: 10.1016/j.jbc.2024.107583 78 RabithaRShivaniSShowketYSudhandiranG

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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Neuman M.W., Hodge H.C

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade