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Chem Commun 12:649650 Kasparov S, Brezov V, Valko M et al (2005) Study of the oxidative stress in a rat model of chronic brain hypoperfusion

Nrf2is a key factor in the control of the expression of genes involved in the regulation of oxidative stress, via the enhanced production of cellular antioxidants

Plant Cell 17, 18661875 (2005)

Thus, changes in peripheral NGF levels may constitute a molecular signal to induce NGF and TrkA transcription in the striatum (CNS)

Experimental evidence from human tumor cell lines derived from either colon, breast, melanoma, osteosarcoma and prostate cancers showed increased exosomal release as the pH was changed from 7.4 to 6.5, supporting the notion that acidic TME is associated with increased exosome production and represents a key phenotype of all human cancers [155]