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Abudayyeh, O

Major barriers to the clinical use of gene therapy, however, include transfection efficiency, the creation of long-term effects, the difficulty of controlling cell proliferation, ectopic transfection, disease transmission, patient-specific dose responses, immune reactions against viral proteins, possible side effects, and ethical issues [87, 88]

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siRNAs are divided into two primary subtypes based on where they come from: endogenous siRNAs (endo-siRNAs), which are primarily transcribed from transposable elements (TEs) and originate from the host genome, and exogenous siRNAs (exo-siRNAs), which are derived from external nucleic acids introduced artificially or through viral infections [26, 27]

The broad range of spirulina's effects is primarily due to the presence of numerous bioactive compounds

Another innovative biophysical therapeutic agent, S-1226, employs carbon dioxide (CO 2 )-rich air in combination with aerosolized perfluorocarbons (PFOB) to promote airway dilation, enhance mucus clearance, and improve blood oxygenation