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GGT AND PULMONARY ARTERIAL HYPERTENSION Increased oxidative stress plays a crucial role in the development and progression of pulmonary hypertension

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Moreover, QUE triggered lysosomal activation by promoting the nuclear translocation of EB and activating the transcription of lysosomal genes

Cell Cycle 10 , 38123813 (2011)

As previously discussed, aerosolized A1AT has a positive impact on neutrophil-mediated killing of P

The discovery of apoE Christchurch and the beneficial effect of the hybrid apoE2 + Christchurch variant in AD mouse models represent major breakthroughs in the field and could accelerate the development of clinical trials to assess the efficacy of AAV-mediated apoE therapy in AD [236]