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The oxidized form of glutathione (glutathione disulfide), which is generated during the reduction of hydroperoxides by GPX4, is recycled by glutathione reductase and NADPH/H +

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For instance, thyroid cancer is associated with the increased presence of Clostridiaceae , Neisseria , and Streptococcus , whereas in patients with thyroid nodules, a relative increase of Streptococcus and Neisseria compared to healthy controls was observed (235)