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In general, evidence from RCTs does not show that vitamin B12 supplementation alone or with folic acid, vitamin B6, or both for 1 to 2 years improves cognitive function in older adults with or without dementia, mild cognitive impairment, or Alzheimers disease, even though supplementation lowers homocysteine levels [93-96]

doi: 10.1001/jama.2013.280490

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And the single-lab concentration of the existing evidence means that what we have is not what scientists would call a robust, independently verified evidence base

By getting a shot you are bypassing the GI tract and allowing for 100% absorption into the body straight into the cells