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The protein was extracted from cells by resuspending the pellet with 20 mM HEPES pH 8.0, 150 mM NaCl, 2 g ml 1 aprotinin, 2 g ml 1 pepstatin, 2 g ml 1 leupeptin, 1 mM phenylmethanesulfonyl fluoride (PMSF), and solubilized with 1% (w/v) n-dodecyl--D-maltoside (DDM

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Iron deficiency anaemia is more likely in people with heavy menstrual bleeding, those following vegan or vegetarian diets, or those with malabsorption conditions and calorie restriction may compound these risks if iron-rich foods are reduced

This suggests a very good safety and tolerability profile indistinguishable from placebo in those trial settings

GnRH agonists are synthetic hormones that mimic natural hormones from the hypothalamus to treat gynaecological conditions like heavy periods, fibroids, and endometriosis

Poor oral and dental health and oral infections can contribute to blood clots