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Limitations Copper chelation strategies have exhibited potential in the treatment of AD

Since 90% of the bodys serotonin originates in the gut, modulating enteric serotonin production could influence central serotonergic tone through vagal afferents that relay gut signals to brain serotonin-producing raphe nuclei

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Wysocki J, OrtizMelo DI, Mattocks NK, Xu K, Prescott J, Evora K, et al

These findings underscore the importance of targeting pathways involved in oxidative stress and ferroptosis to prevent or treat heart failure