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Rat studies have noted embryofetal mortality, structural abnormalities, and alterations to growth at maternal exposures below the maximum recommended human dose (MRHD) based on exposure AUC

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In the absence of impaired kidney function, an elevated MMA level in conjunction with elevated homocysteine suggests either a vitamin B 12 deficiency or a combined vitamin B 12 and folate deficiency (32)

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Symptoms of anemia include fatigue, shortness of breath, dizziness, and pale skin

When consumed in excess, a few different B vitamins can have specific side effects