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30 Three of the four RCTs of B12 alone used oral B12 (1000 g per day) and one used i.m

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Most experiments were performed in HCT-116 cells, with selected validation in HT-29 cells, and the findings may not be generalizable to the metabolic heterogeneity of colorectal cancer

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As a potent ferroptosis inducer and chemotherapeutic drug carrier for AML treatment, Yu et al (169) showed that the ferroptosis-inducing nanomedicine glutathione-capped ferrite nanoparticles successfully overcame AML resistance