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[6] [7] [8] [10] [11] [12] IDH1 interacts with isocitrate and a divalent metal ion cofactor, typically Mg 2+ or Mn 2+ , which plays a crucial role in stabilizing the negatively charged intermediates formed during the enzymatic reaction

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Glutathione causes a massive and selective induction of plant defense genes

Zhou Y, Miles JR, Tavori H, Lin M, Khoshbouei H, Borchelt DR, Bazick H, Landreth GE, Lee S, Fazio S, Notterpek L (2019) PMP22 regulates cholesterol trafficking and ABCA1-mediated cholesterol efflux

This matters because delayed gastric emptying can raise aspiration risk

Targeting the ubiquitin-proteasome pathway to overcome anti-cancer drug resistance