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D-TERMINED, a phase 1 trial in newly diagnosed high-grade glioma with temozolomide, radiation, and minocycline followed by adjuvant minocycline/temozolomide

Future research should focus on unraveling details on the dynamics of the BBB, and how alterations in BBB affect the nervous system, further leading to various disorders

TNF- suppresses EBV reactivation through GPX4-mediated antioxidant activity, highlighting the importance of glutathione-dependent pathways in limiting viral lytic activation

10.1002/art.34483 95

Even though our data show that both agents separately caused cell damage, ethanol potentiated the mucosal injury caused by TNBS, an event that was accompanied by a significant depletion of mucosal GSH levels, suggesting that GSH limitation contributed to enhanced cell injury (Table 1)

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