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In a phase 2a clinical trial, peresolimab treatment led to a significantly greater reduction in the DAS28-CRP score at week 12 compared to placebo, which raises the possibility to control autoimmune inflammation by influencing the PD-1 inhibitory pathway (101)

Resende, M

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Recent studies highlight the effectiveness of NAC in mitigating ROS, fostering pro-repairative microenvironment and enhancing the osteogenic potential and immune regulatory function of cells, which offers a promising role in the treatment of bone injuries and bone tissue engineering (Supplementary Figure S1B)

10.1007/s10911-008-9104-6 95 WuT.QiW.ShanH.TuB.JiangS.LuY.et al (2022)

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