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This is especially crucial for patients with neurological symptoms, which can easily become permanent if under-treated long enough

Injection site rotation Rotating injection sites prevents lipodystrophy (tissue changes at injection sites) and ensures consistent absorption

Severe anemia Severe describes severity, not etiology

Regarding absorption , it's worth noting that crystalline B12 found in supplements is already in free form and does not require separation from food proteins by stomach acid, unlike B12 naturally present in food

A pilot study of 12 patients with chronic knee pain showed relief in 7 of them for more than 6 months after a single injection

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