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Thus, it was concluded that the stronger effect of HCV-3a core protein was a plausible reason for the higher prevalence and severity of steatosis in HCV-3a infection.[43] Current treatment in HCV-3 Peginterferon (PEG-IFN) -2b (1.5 mg/kg/week) plus ribavirin (RBV) (800-1400 mg/day) or PEG-IFN -2a (180 mg/week) plus RBV (800 mg/day) for 24 weeks have been the established standard of care regimens for patients with HCV-3.[44] However, the optimal administration of PEG-IFN and RBV, especially the duration, has still not been clearly established

Carnitine supplementation in dialysis patients remains an unsolved issue, whereas carnitine deficiency in plasma and tissues (skeletal muscle) is obvious in many patients after several years on hemodialysis treatment