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Description

Parkinsons disease affects the central nervous system and is defined by symptoms such as tremors

Alignment of SjTrx1i and SjTRP14

skin firmness

Notably, similar inhibitions were observed both with the wild type enzyme and its cysteine mutants, suggesting that thiol conjugation is dispensable for GST inactivation by auronofin in contrast to other described targets 103

Studies suggest that maintaining adequate glutathione levels helps preserve the integrity of neural membranes and supports the cellular processes involved in synaptic transmission

Nrf2 transcriptionally activates GGT [29], which plays a key role in glutathione homeostasis by breaking down extracellular glutathione into its constituent parts, which can be taken up by the cell for intracellular glutathione synthesis [30]