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HER2 positivity is a pivotal determinant of treatment strategies, particularly with the use of targeted therapies such as trastuzumab, which significantly improves survival outcomes in patients with HER2-positive tumors

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Temporal single-cell tracing reveals clonal revival and expansion of precursor exhausted t cells during anti-pd-1 therapy in lung cancer

Alzheimers is a common cause of dementia in those over 65 years of age but people as young as 48 have been diagnosed with mild cognitive impairment (MCI)

Three-dimensional structure of a pyridoxal-phosphate-dependent enzyme, mitochondrial aspartate aminotransferase

Demonstrating that ferroptosis is a driver of disease in CF offers the opportunity to intervene therapeutically and in this study we showed that the GSH prodrug N-acetylcysteine (NAC) was able to recover the levels of GSH back to normal and alleviate erastin-induced ferroptotic cell death