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Assuming D-retro-inverso A 40 (DRI-A 40 ) peptides and D-retro-inverso A 42 (DRI-A 42 ) peptides to form similar assemblies as (L-) A 40 and (L-) A 42 peptides, respectively, one can conjecture two mechanisms by that the DRI peptides could reduce the concentration of toxic A-oligomers

Pathway analysis on gene sets and ordered vector of genes (Gene Set Enrichment Analysis) was performed with clusterProfiler 93 (v4.6.2) and fgsea 94 (1.24.0) R packages using Gene Ontology (GO) biological process (2022-07-01) and Kyoto Encyclopedia of Genes and Genomes (KEGG, 2023) pathway datasets

Whether antimicrobials are dispensed in prescription or herbal form, they can induce in Lyme patients a Herxheimer reaction a flare of inflammatory chemicals, called cytokines, that are produced as infection dies off

With regard to endogenous antioxidant function, it is important to note that just as IR pathology occurs through the parallel events of free radical production and calcium dyshomeostasis, exercise-induced protection mediates simultaneous protection through redundant mechanisms that offer tandem levels of protection

Free Radic Res 50:126142 Marc M, Brown DS, Capell T, Figueras X, Tiburcio AF (1995) Rapid high-performance liquid chromatographic method for the quantitation of polyamines as their dansyl derivatives: application to plant and animal tissues

Thanks also go to Instrumentation Center at NTHU for Bruker ElEXSYS E580 EPR analysis