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Recent advances in targeting the undruggable proteins: from drug discovery to clinical trials

10.1073/pnas.0812600106 Proc Natl Acad Sci U S A

Sofroniew, M

The worldwide costs of dementia 2015 and comparisons with 2010

Receptor tyrosine kinase mediated resistance to MAPK targeted therapies and activation of the inflammatory signaling associated with immune therapy involves transitions along this differentiation trajectory, which lead to increased sensitivity to ferroptosis