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This endocrine-like axis, linking adipose tissue, endothelial dysfunction, and atherosclerosis, may explain in part the ramifications of obesity-caused atherosclerosis

PAC1R, VPAC1R, and VPAC2R) have been identified, and they can activate diverse pathways, including the signaling through AC (169)

In this review, we summarize diverse regulatory mechanisms of SLC7A11 in cancer, discuss ferroptosis-dependent and -independent functions of SLC7A11 in promoting tumor development, explore the mechanistic basis of SLC7A11-induced nutrient dependency in cancer cells, and conceptualize therapeutic strategies to target SLC7A11 in cancer treatment

Together, these single-cell transcriptomic analyses support potential roles for TrkB signalling in neuron-to-glioma synaptic biology as well as glioma-to-glioma network formation, with TrkB correlated with distinct processes in astrocyte-like and oligodendroglial-like cellular subpopulations

10.1016/j.biomaterials.2017.04.029 [DOI] [PubMed] [Google Scholar] 12.Lee Y et al

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