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Current treatment guidelines for severe symptomatic chronic hyponatremia recommend empiric intervention with intravenous 3% NaCl to increase serum sodium levels by 46 mmol/L within the first 24 h 3,4,6,7,8,9

This could include vitamin B12 injections for pernicious anaemia, better glucose control in diabetes, or changing your cholesterol medication for one which is not a statin

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The change in serum sodium levels at 1, 6, 12, and 24 h were not different, however, at 48 h, the proactive group exhibited a higher but still safe change in serum sodium levels compared to the reactive group (10.3 3.6 mmol/L vs

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Taken together, it seems that B12 supplementation would be effective for migraine attack alleviation