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Some individuals might use up their B12 reserves quicker than others, requiring more frequent injections

(2018) Oral vitamin B(12) versus intramuscular vitamin B(12) for vitamin B(12) deficiency

Repa, J

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The most prevalent symptoms of vitamin B12 deficiency are neurologic, such as paraesthesia in hands and feet, muscle cramps, dizziness, cognitive disturbances, ataxia, and erectile dysfunction, as well as fatigue, psychiatric symptoms like depression, and macrocytic anaemia." Even if a person gets enough vitamin B12 in their diet, some underlying health conditions can affect the absorption of vitamin B12 in the gut

This approach was chosen because clinical cutoffs are based on disease-related epidemiological data and biomarkers unrelated to fertility