According to the European Society of Cardiology (ESC) 2016 practice guidelines on cancer therapy and cardiovascular toxicity, the incidence of cardiac dysfunction and heart failure caused by sorafenib can be as high as 4% to 8% [6]
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In order to achieve the purpose, the technical scheme of the invention is as follows: the high-stability reduced glutathione for injection is characterized in that: when the amount of the reduced glutathione is 0.6g, the formula components are as follows: reduced glutathione 0.6g Adjusting the pH of the solution to 6.0-7.0 with 10% sodium hydroxide solution Adding water for injection to 2g When the amount of the reduced glutathione for injection is 1.0g, the formula components are as follows: reduced glutathione 1.0g Adjusting the pH of the solution to 6.0-7.0 with 10% sodium hydroxide solution Adding water for injection to 3.3g When the reduced glutathione for injection is 1.5g, the formula components are as follows: reduced glutathione 1.5g Adjusting the pH of the solution to 6.0-7.0 with 10% sodium hydroxide solution Adding water for injection to 5.0g Wherein, in the liquid preparation process, nitrogen is continuously filled in the liquid preparation and filling processes to keep the oxygen content in the solution below 1.5 ppm
Ice pick scars tend to be very tough to treat, and often require persistent, aggressive treatment
Serious side effects are extremely rare
The role of these enzymes in pyrethroid resistance has been validated in vivo utilizing heterologous expression in Drosophila (Pavlidi et al., 2012
