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Furthermore, the expression of the transcription factor p53 and the cyclin-dependent kinase inhibitor p21 induced by bilirubin inhibits the proliferation of established smooth muscle cells (SMC) and neoplastic endothelial proliferation (104, 105)

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Protein thiol homeostasis: Glutathione maintains proteins in their reduced (functional) state through S-glutathionylation, a reversible post-translational modification that regulates protein activity under oxidative stress [2]

Vitamin B12, or cobalamin, is essential to many bodily processes

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199-201 On the other hand, dietary patterns associated with reduced male fertility are characterized by high intake of red and processed meats, sweet drinks and snacks, trans- and omega-6 fatty acids, and overall calories, as well as low intake of fiber, fish, fruits and vegetables, and nuts and seeds