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Shang, L

In animal models (and in vitro work), it has been shown to release GH without substantially raising other hormones like ACTH or cortisol, which means less off-target hormonal disturbance

Still, weve also noted reports of mishaps

[PubMed: 27295182] 131

Insulin sensitivity shifts become more likely when multiple growth-promoting compounds are used simultaneously

This selectivity allows researchers to isolate GHS-R1a-specific signaling from broader multi-receptor agonist effects in both in-vitro cellular assays and in-vivo preclinical animal models