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Healthy NP tissue generally contains two cell types, depending on age and species: notochordal cells that play an important role in IVD development, growth, and homeostasis, and the nucleopulpocytes that maintain the IVD post development (Clouet et al., 2019)

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The promise it holds is tantalizing, but it is coupled with a responsibility to tread carefully in the realm of experimental therapeutics

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[15] [18] If you suspect your B12 supplement is causing diarrhoea, consider trying an alternative formulation or a different brand with fewer excipients

Through SA--gal staining, we found that FOXO4-DRI also reduced the number of positive cells in the aorta of D-galactose induced aged mice (Figure 2C)