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doi: 10.1038/nri3399 192 ChangYSyahirahRWangXJinGTorregrosa-AllenSElzeyBDet al

G-S-S-G = oxidized glutathione

Alkylamine-based degraders functionally depend on FBXO22 To explore the potential generalizability of exploiting FBXO22 for targeted protein degradation, we extended our experiments to two recently reported primary alkylamine-tethered degraders targeting either NSD2 or XIAP, as well as a set of alkylamine-tethered analogues targeting BRD4 (Fig

Prior to joining the team, she worked as Us Weeklys Beauty and Style Editor, where she stayed on the pulse of pop culture and broke down celebrity beauty routines, hair transformations, and red carpet looks