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The Nrf2 pathway responds to ROS by activating the transcription of phase II detoxification enzymes

The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma

centrifuge at 10,000 g for 10-15 min at 4C, and remove the supernatant for subsequent reduction of glutathione assay

This article summarizes the data on analyses performed in the CSF of patients diagnosed with PD compared with controls, with regard to: (1) concentrations of neurotransmitters (mainly monoamines and their metabolites), neuromodulators, and related substances as possible biological markers of the disease itself or its complications

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