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Hence, Smartamine is resistant to the rumen pH, but is soluble in lower pHs, such as the post-ruminal environment, being undegradable in the rumen and immediately released in the abomasum

Diagnosis of Vitamin B12 Deficiency The diagnosis of vitamin B 12 deficiency has traditionally been based on low serum vitamin B 12 levels, usually less than 200 pg per mL (150 pmol per L), along with clinical evidence of disease

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J Urol 169:22102215 Antonini A, Yegin A, Preda C, Bergmann L, Poewe W, investigators Gs, coordinators (2015) Global long-term study on motor and non-motor symptoms and safety of levodopa-carbidopa intestinal gel in routine care of advanced Parkinsons disease patients

This is the bidirectional communication system between the gastrointestinal tract and the central nervous system