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Moreover, elevated TFR expression in lung cancer cells undergoing EMT (epithelial-mesenchymal transition) has been demonstrated to facilitate iron acquisition and confer heightened sensitivity to ferroptosis in these cells [30] (Fig

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It might be the clue to examine the dMMR-associated clinical biomarkers predicting the anti-tumor efficacy of immunotherapies for the patients with unresectable HCC

Most importantly, glutathione in its finished form cannot be taken up by the cells of the body due to an unfavorable concentration gradient

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