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Future research will focus on decoding metabolic regulationsuch as CSF1R-mediated resting-state energy metabolism and AMPK/mTOR-controlled activated-state metabolic remodelingand targeting BDNF neurotrophic or TNF- pro-inflammatory signaling to develop precision therapies for neurodegenerative diseases, leveraging microglial metabolic-immunological crosstalk (Salter and Stevens, 2017)

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These regions encompass non-coding RNA genes, which possess the potential for transcription, as well as regulatory elements that are not transcribed

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10.3389/fphar.2021.719880 34 LuoL

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Population genetic studies have investigated how schistosome populations have changed following PZQ MDA ( Supplementary Table 1 )

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Although some studies confirm the feasibility of exempting patients who achieve pCR after neoadjuvant systemic therapy under rigorous evaluation using ultrasound or MRI, 323,326,327 this approach is constrained by regional development levels and technological disparities

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