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doi: 10.3389/fchem.2020.583272 Received 14 July 2020 Accepted 13 October 2020 Published 12 November 2020 Volume 8 - 2020 Edited by Chun Xu, The University of Queensland, Australia Reviewed by Junfeng Zhao, Jiangxi Normal University, China

This aligns with the clinical correlates observed by Shrestha et al., which indicate that high baseline redox scores predict poor immunotherapy responses [306]

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Lpez-Mirabal H.R., Winther J.R

NLRP3 is an inflammasome, and its activation is closely related to tumorigenesis and tumor-related inflammation (35)

Hyperlipidemia treatment were given to group 2 (HCD) and group 3 (HCD+VOO) as described above in experimental design

Because high ionic strength can affect the stability of some proteins [40], weak exchangers might be more suitable for proteins that do not require an extreme pH for binding