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The CD44 transmembrane glycoprotein family adds new aspects to these roles by participating in signal-transduction processes not only by establishing specific transmembrane complexes, but also by organizing signalling cascades through association with the actin cytoskeleton

Subsequently, 10 g/mL of LPS (Sigma-Aldrich) was added to the cultures, and the cells were incubated for an additional 6 hour to induce the expression of proinflammatory genes