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Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

Their primary mode of action involves binding to ergosterol, a key sterol component of fungal cell membranes, leading to the formation of pores that disrupt membrane integrity and cause leakage of intracellular ions such as Na + , K + , H + , and Cl - , ultimately inhibiting fungal growth (Gray et al., 2012

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Hydration effects might last a few days, while vitamin benefits could last one to two weeks

J Affect Disorder 20;143(1-3):348