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But again, its important to remember that IV therapy is not a magic cure-all

PCS activates NADPH oxidase and the production of ROS via the protein kinase C and PI3K signaling pathways, which lead to the expression of inflammatory cytokines in renal tubular cells and the mediation of renal fibrosis [109]

Low glutathione levels send signals that trigger cell death (apoptosis)

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However, several articles have commented on the situation, analyzed the reasons for the trials failure and discussed potential future directions for development