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of healthy controls, DCIS, and invasive breast cancer tissues, identified significant changes in methylation profiles across different stages of disease progression ( 3.1 DNA methylation: a critical epigenetic regulator of TNBC DNA methylation is one of the critical epigenetic factors involved in the regulation of gene expression and genomic stability and is biologically necessary for the maintenance of many cellular functions ( As a critical regulator of gene expression, distinct methylation patterns can underlie the onset of various conditions, including cancer ( Figure 2 )

Immune checkpoint of B7H3 in cancer: from immunology to clinical immunotherapy

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These molecules are often mentioned in the same breath, leading many people to ask if they are the same thing or if one is a version of the other