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Bipolar depression was included in a recent randomized controlled pilot study assessing the safety and feasibility of KMT as adjunctive therapy, and reported safety and feasibility with excellent adherence and maintenance of ketosis (mean BHB 0.88 0.99 mmol/L for 12 weeks) (32)

doi: 10.1073/pnas.1201627109 110 ViljoenE.VisserJ.KoenN.MusekiwaA

Bacterial isolation and taxonomic identification Root samples collected from the Ca800 treatment were used for bacterial isolation, as the Ca-enriched taxa (ASVs) were identical to those found in the Ca300 and Ca400 treatments, but their relative abundances were highest in the Ca800 treatment

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Furthermore, BSO alone did not induce any cytotoxicity in either of the gill cells