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1 Introduction Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by deficits in social communication and the presence of restrictive and repetitive behaviors ( Although ASD is considered a common disorder, the exact etiology remains unknown ( The imbalance between neurotransmitters with excitatory and inhibitory properties is recognized as an etiological factor for ASD ( + K + 2Cl cotransporter 1 (NKCC1) and K + Cl cotransporter 2 (KCC2) were significantly correlated with GABAergic signaling ( Probiotics have the potential to reduce the symptoms of ASD by modulating neuroactive compounds

This measure not only helps determine baseline fitness levels but is also predictive of postoperative outcomes such as disease recurrence and overall survival

Majtan T, Koich V, Kruger WD

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The primary mechanisms behind these effects involve the activation of the caspase-3 and 7 pathways, inhibition of histone deacetylase (HDAC), and an enhancement of cisplatins cytotoxic effects [237]