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Studies have demonstrated that curcumin not only effectively inhibits the growth of C

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An assessment of the role of redox cycling in mediating the toxicity of paraquat and nitrofurantoin

A brief survey of these targets follows: Cysteines that were liganded by both haloacetamide 11 and a subset of BDHI analogs include C27 of cleavage and polyadenylation specificity factor subunit 3 (CPSF3), C708 of importin-4 (IPO4), C906 of mitochondrial monofunctional C1-tetrahydrofolate synthase (MTHFD1L, also known as formyltetra-hydrofolate synthetase), and C140 of glutathione S -transferase C-terminal domain-containing protein (GSTCD)